Fmoc-(R)-2-amino-2-methylhex-5-enoic acid

Fmoc-(R)-2-amino-2-methylhex-5-enoic acid - Names and Identifiers

Name	(R)-N-Fmoc-2-(3'-butenyl)alanine
Synonyms	FMoc-α-Me-D-Gly(Butenyl)-OH (R)-N-Fmoc-2-(3'-butenyl)alanine Fmoc-(R)-2-amino-2-methylhex-5-enoic acid (R)-2-(Fmoc-amino)-2-methylhex-5-enoic acid (9H-Fluoren-9-yl)MethOxy]Carbonyl Alpha-Methyl-D-Gly(Butenyl)-OH (2R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methyl-5-hexenoic acid (R)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-2-Methylhex-5-enoic acid (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylhex-5-enoic acid
CAS	1311933-82-0

Fmoc-(R)-2-amino-2-methylhex-5-enoic acid - Physico-chemical Properties

Molecular Formula	C22H23NO4
Molar Mass	365.42
Density	1.203±0.06 g/cm3(Predicted)
Boling Point	575.6±45.0 °C(Predicted)
pKa	3.95±0.11(Predicted)
Storage Condition	Sealed in dry,Room Temperature

Fmoc-(R)-2-amino-2-methylhex-5-enoic acid - Introduction

(R)-N-fluorenylmethoxycarbonyl-2-(3 '-butenyl)-L-alanine, also known as Fmoc-L-oxalyl-3-butenyl amino acid, is an organic compound. Its structure contains fluorene ring, 3 '-butenyl group and L-alanine group.

Nature:
(R)-N-Fluorenylmethoxycarbonyl-2-(3 '-butenyl)-L-alanine is a white to pale yellow solid. It has a high melting point and solubility, soluble in some organic solvents such as methylene chloride and carbon disulfide.

Use:
This compound is mainly used for protecting groups in peptide synthesis. It can be used in the biopharmaceutical field as a starting material for the synthesis of peptides, for the formation of dihydropyrrolyl groups, for the protection of other amino acid groups. It can also be used to synthesize polypeptides, study biological activities and prepare drugs.

Preparation Method:
(R)-N-fluorenylmethoxycarbonyl-2-(3 '-butenyl)-L-alanine can be prepared by chemical synthesis. A common preparation method is to react fluorenecyl chloride with L-alanine and 3-butenylamine in the corresponding organic solvent, and then obtain the target product by crystallization or purification.

Safety Information:
This compound is relatively safe under normal operating conditions, but it is still necessary to pay attention to personal protective measures, such as wearing protective gloves and safety glasses. Proper laboratory practices and operating procedures should be followed for the use of any chemical. In addition, understand the toxicity and danger of the compound, and take appropriate measures when handling to ensure the safety of individuals and the environment.

Last Update：2024-04-09 20:52:54